a Record control number 000263246400012

a ISSN 0004-3591

a Original cataloging agency NEU GrandLibrary

a Language code of text/sound track or separate title eng

a Classification number WE 544

b Item number .I53 2009

a Personal name Wilson, Floranne C.

h Medium Electronic Document

a Title Incidence and Clinical Predictors of Psoriatic Arthritis in Patients With Psoriasis: A Population-Based Study .

c Statement of responsibility, etc Floranne C. Wilson, Murat Icen, Cynthia S. Crowson, Marian T. McEvoy, Sherine E.Gabriel, Hilal Maradit Kremers.

c Date of publication, distribution, etc 2009.

b Name of publisher, distributor, etc Wiley-Liss,

a Summary, etc Objective. To determine the incidence and disease-specific predictors of clinically recognized psoriatic arthritis (PsA) in patients with psoriasis. Methods. We identified an incidence cohort of psoriasis subjects age;2:18 years diagnosed between January 1, 1970 and December 31, 1999 in a population-based setting. Psoriasis diagnoses were validated by confirmatory diagnosis in the medical record. Incident and clinically recognized PsA subjects were classified according to the Classification of Psoriatic Arthritis (CASPAR) criteria. Cox proportional hazards models were used to identify predictors of PsA within the psoriasis cohort. Results. The psoriasis incidence cohort comprised 1,633 subjects. Of these, 40 were diagnosed with PsA concurrently with psoriasis and were excluded from analysis. The remaining 1,593 psoriasis subjects had a mean age of 43 years and 50% were men. Over 20,936 person-years of followup, 57 subjects were clinically recognized with new-onset PsA, with a cumulative incidence of 1.70% (95% confidence interval [95% CI] 1.0-2.3%), 3.1% (95% CI 2.2-4.1%), and 5.1% (95% CI 3.7-6.6%) at 5, 10, and 20 years following psoriasis incidence, respectively. Psoriasis features associated with higher risk of PsA were scalp lesions (hazard ratio [HR] 3.89, 95% CI 2.18-6.94), nail dystrophy (HR 2.93, 95% CI 1.68-5.12), and intergluteal/perianal lesions (HR 2.35, 95% CI 1.32-4.19). Calendar year was not associated with risk of PsA (P = 0.15), indicating that the likelihood of PsA in psoriasis subjects did not change over time. Conclusion. In this population-based study, <10% of patients with psoriasis developed clinically recognized PsA during a 30-year period. Psoriasis features associated with a higher likelihood of PsA were nail dystrophy, scalp lesions, and intergluteal/perianal psoriasis.

a Topical term or geographic name as entry element Rheumatology.

a Topical term or geographic name as entry element Near East University Article

a Topical term or geographic name as entry element Yakın Doğu Üniversitesi Makale

a Topical term or geographic name as entry element Rochester Epidemiology Project

a Topical term or geographic name as entry element Joint Complaints

a Main entry heading Arthritis & Rheumatism-Arthritis Care & Research

g Relationship information FEB 15 2009, Vol 61 Issue 2, p233-239

x International Standard Serial Number 0004-3591

u Uniform Resource Identifier http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1002/art.24172